Isotretinoin (Accutane®) is a treatment that is mostly used to treat acne. It is obtained from Vitamin A and modifies the function of the sebum glands; hence the sebum production is reduced. It is a medication that requires a prescription and has a lot of known side effects and contraindications, including pregnancy, breastfeeding, and alcohol intake.
The number of cases where acute liver damage is triggered by the combination of alcohol and Tretinoin is very low; however, the normal function of this organ is modified.
Here you have the most known facts about the interaction of Isotretinoin and Alcohol:
- Alcohol and Isotretinoin are metabolized in the liver; hence, it will double this organ’s efforts to degrade them, possibly leading to an inflammation or liver insufficiency.
- If the liver stops functioning at its full capacity, the blood levels of the Isotreitoin will be higher, and the chances of elimination will be decreased.
- If you consume Isotretinoin and alcohol simultaneously and daily, you must take a blood test to determine your transaminase levels. They will likely be elevated, meaning your liver is not working properly. If this happens, you must consult with your physician, indicating that your medication must be suspended until further notice.
Does this mean I can’t drink any alcohol while on Tretinoin?
Yes and no, a huge amount of alcohol is contraindicated, but a small and occasional alcohol intake can be allowed. In any case, you must consult with your physician if you are under this treatment.
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About the Author: Dr. Angelica Parra is a Licensed Medical Doctor from Venezuela and is currently taking a Master’s degree in Dermatology. She specialized in Aesthetic Medicine and completed Advanced Training in Non-surgical Facial Rejuvenation in Miami, Florida. She has specialized in applying Botox, dermal fillers, skin tightening treatments, and since then, she has worked on cruise ships as an Aesthetic Doctor.